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Best Paper Award

This to certify that International Research and Publications in Medical Sciences (IRPMS) editorial team has considered to present the best paper award to the corresponding author Kristine Joy G. Boholst, Noli A. Cabildo, David Vi for publishing his outstanding research paper in IRPMS, Volume-3, Issue-4, Oct-Dec entitled as 1. FACTORS FOR TUBERCULOSIS TREATMENT RELAPSE AMONG PATIENTS PREVIOUSLY TAKING CATEGORY 1 STANDARD TUBERCULOSIS TREATMENT REGIMEN IN SELECTED MUNICIPALITIES OF ILOCOS SUR.

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Abstract

9. Male infertility and 47,XYY syndrome: Case Report.

Salil N. Vaniawala, Pankaj K. Gadhia,

Int Res Pub Med Sci,2015;1(4):46-49

ABSTRACT

Background: 47,XYY syndrome is a sex chromosomal anomaly observed in humans with prevalence rate of 1 in 1000 male live births. This anomaly is frequently associated with male infertility. Method: A retrospective study was carried out on infertile male referred to our diagnostic laboratory for chromosomal analysis. In the current study, six cases of infertile male with azoospermia and oligospermia were studied in detail out of total 562 infertile males. The study was extended using FISH technique and confirmed presence of extra Y chromosome in all six cases. Results: Chromosomal analysis revealed nonmosaic karyotype of 47, XYY in all six cases. In these cases, presence of extra Y chromosome was confirmed in metaphase chromosome and interphase cell by FISH analysis using fluorescence labelled X and Y centeromeric probes. Conclusion: The 47,XYY syndrome is relatively uncommon and due to non-phenotypic abnormalities it can be missed. Accurate diagnosis with karyotype and FISH will be helpful in management of infertile males.

Key-words: 47,XYY syndrome, G-banding, Karyotype, FISH, Male infertility.

HOW TO CITE THIS ARTICLE:

Pubmed Style

Vaniawala SN, Gadhia PK. Male infertility and 47, XYY syndrome. Int Res Pub Med Sci 2015; 1(4):46-49.

Web Style

Vaniawala SN, Gadhia PK. Male infertility and 47, XYY syndrome. Int Res Pub Med Sci. http://irpms.com/home/article_abstract/112 [Access: Jan 15, 2015].

AMA (American Medical Association) Style

Vaniawala SN, Gadhia PK. Male infertility and 47, XYY syndrome. Int Res Pub Med Sci. 2015; 1(4):46-49.

Vancouver/ICMJE Style

Vaniawala SN, Gadhia PK. Male infertility and 47, XYY syndrome. Int Res Pub Med Sci. 2015; 1(4):46-49.

Harvard Style

Vaniawala SN, Gadhia PK.(2015) Male infertility and 47, XYY syndrome. Int Res Pub Med Sci. 1(4):46-49.

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