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Kavita Yadav, Kishori Lal Meena, Anshul Gupta, RakeshGarg, Int Res Pub Med Sci,2015;1(3):40-45
Kavita Yadav, Kishori Lal Meena, Anshul Gupta, RakeshGarg,
Int Res Pub Med Sci,2015;1(3):40-45
Background: Aphthous ulcer is one of the most common diseases of the oral cavity with no known effective treatment so far, which could cause severe discomfort in patients. There are few clinical trials where Aloe Vera (AV) has been used in the treatment of oral diseases such as oral lichen planus, recurrent aphthous stomatitis, oral pemphigus, herpetic stomatitis, radiation induced mucositis. Aims & Objectives: The aim of this study is to evaluate topically administered AV gel on oral cavity minor aphthous healing. Methods: The retrospective multiple level clinical trials study done on having recurrent aphthous stomatitis patients comes for regular checkup in Department of Dentistry, S.P. Medical College Bikaner, Rajsthan. The sample population was recruited from patients visiting the Dentistry Clinic who had given written consent to participate in this double-blind (phase II) clinical trial from January 2014 till December 2014. Results: The present study shows that the healing times for pain and lesions (lesion diameter < 1 mm) in the AV-treated group were signi?cantly lower than in the control group. Conclusion: The presnt study shows that AV 2% oral gel is not only effective in decreasing the recurrent aphthous stomatitis patient's pain score and wound size but also decreases the aphthous wound healing period.
Key-words: Aloe vera, Visual Analogue Scale (VAS), Aphthous ulcer, Wound Healing, Oral Disease.