7. A Study Of Efficacy Of Acyclovir In Treatment Of Pityriasis Rosea

B.C. Ghiya, Ashok Kumar, Prasoon Soni, Lokesh Chawala, Anukriti Shrivastya

ABSTRACT

Background: Pityriasis rosea (PR) is an acute inflammatory skin disorder. Though self-limiting, but the bothersome symptoms often have a significant impact on the quality-of-life of patients. Despite active labor for nearly one & half century by generations of researchers, the etiology of Pityriasis rosea fails to be demystified. Aims: The aim of present study of the efficacy and safety of Acyclovir in treatment of Pityriasis rosea. Material & Methods: A prospective controlled study was conducted on 60 patients of Pityriasis rosea attending outdoor patient department of Dermatology, Venereology and Leprosy, SP Medical College and PBM Hospital, Bikaner. The cases were diagnosed on the basis of typical clinical presentation. The characteristic orientation of the discrete circular or oval lesions along lines of skin cleavages, parallel to the ribs with peripheral collarette scaling with central clearance on at least two lesions. Results: Most common age group was 12-20 years where total 58.3% patients were found followed by 21-30 (25%), 31-40 and >40 (8.3% each). Out of total 30 patients of study group 20 were males while in the control group out of total 30 patients, 19 were male and this difference was found statistically insignificant (p>0.05). Mother patch was present in 50% and 30% of patients in the study and control groups respectively and this difference was also found statistically insignificant (p>0.05). Conclusion: Acyclovir 800mg 5 times a day for 7 days helps in the reduction of duration of disease and morphological parameter of Pityriasis rosea in terms of erythema, scaling and induration as compared to the control group however a larger study should be performed to confirm these findings.

Key-words: Pityriasis rosea, Acyclovir, Skin diseases, Case control.

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