e-ISSN 2395-3950, p-ISSN 2395-440X
Severity: 8192
Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 132
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 294
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 168
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 237
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 317
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: 8192
Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice
Filename: drivers/Session_files_driver.php
Line Number: 358
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 282
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: session_set_cookie_params(): Session cookie parameters cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 294
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 304
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 314
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 315
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 316
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 317
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: ini_set(): Session ini settings cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 375
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: session_set_save_handler(): Session save handler cannot be changed after headers have already been sent
Filename: Session/Session.php
Line Number: 110
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
Severity: Warning
Message: session_start(): Session cannot be started after headers have already been sent
Filename: Session/Session.php
Line Number: 143
Backtrace:
File: /home1/irpmsom/public_html/application/controllers/Home.php
Line: 9
Function: library
File: /home1/irpmsom/public_html/index.php
Line: 315
Function: require_once
e-ISSN 2395-3950, p-ISSN 2395-440X
This to certify that International Research and Publications in Medical Sciences (IRPMS) editorial team has considered to present the best paper award to the corresponding author Kristine Joy G. Boholst, Noli A. Cabildo, David Vi for publishing his outstanding research paper in IRPMS, Volume-3, Issue-4, Oct-Dec entitled as 1. FACTORS FOR TUBERCULOSIS TREATMENT RELAPSE AMONG PATIENTS PREVIOUSLY TAKING CATEGORY 1 STANDARD TUBERCULOSIS TREATMENT REGIMEN IN SELECTED MUNICIPALITIES OF ILOCOS SUR.
editor@ irpms.com, irpmseditor@gmail.com +91 9427222776
Rahul Saini, Bhawna Sharma, Prem Kumar Verma, Garima Bhutani, Seema Rani
ABSTRACT
Background: There is no other group in pharmacology which truly can replace the role of NSAIDs in daily life as far as pain, inflammation and fever are concerned. But it is also true fact that NSAIDs are associated with lots of ADRs like gastritis, gastric ulcer, gastric perforations, obstructions. The other reported ADRs are cardiac, psychological, dermatological and renal in a small number of patients. Method: This Pharmacovigilance study was conducted for assessing the ADRs that occur due to NSAIDS in the BPS Hospital, Khanpur Kalan, Sonepat. The study period was of 8 months duration, from April, 2015 to February, 2016. The patients with any adverse event due to NSAIDS, of both genders and all age groups were included in the study. Detailed history of ADR (drug name, dose and frequency, date of onset, pattern), nature of illness for which the drug was taken and recorded. WHO-UMC Causality Assessment scale and Naranjo Algorithm was used for the causality assessment of the ADRs due to NSAIDS. Results: Out of 163 ADRs observed (from April, 2015 to February, 2016) 27 ADRs were due to NSAIDS administration. Out of 27 ADRs, 17 (62.96%) were due to Diclofenac, followed by 6 (22.22%) due to paracetamol, 2 (7.40%) due to Ibuprofen and 1 (3.70%) due to a combination of Diclofenac and Paracetamol. No ADR was found due to nimuslide and etoricoxib, that were prescribed less frequently as compared to Diclofenac and paracetamol. Along with NSAIDs gastroprotective agents, i.e. ranitidine and pantoprazole were prescribed in 9 out of 27 patients. Antibiotics were prescribed to 4 patients along with NSAIDS. Causality assessment was done by WHO UMC Causality Assessment scale and Naranjos algorithm Scale revealed that out of 27 ADRs, 20 were possible and 7 were probable in nature. Conclusion: There is need of continuous vigilance over the adverse drug reactions due to NSAIDs otherwise would result in an unnecessary increase in morbidity and mortality.
Key-words: NSAIDs, ADR, Pharmacovigilance, adverse drug reaction, causality assessment.
HOW TO CITE THIS ARTICLE:
Pubmed Style
Saini R, Sharma B, Verma PK, Bhutani G, Rani S. NSAIDS: The Double Edge Sword- Pharmacovigilance In A Tertiary Care Hospital, Int Res Pub Med Sci. 2016; 2(3) : 6-10.
Web Style
Saini R, Sharma B, Verma PK, Bhutani G, Rani S. NSAIDS: The Double Edge Sword- Pharmacovigilance In A Tertiary Care Hospital, http://irpms.com/home/article_abstract/156 [Access: Oct 15, 2016].
AMA (American Medical Association) Style
Saini R, Sharma B, Verma PK, Bhutani G, Rani S. NSAIDS: The Double Edge Sword- Pharmacovigilance In A Tertiary Care Hospital, Int Res Pub Med Sci. 2016; 2(3) : 6-10.
Vancouver/ICMJE Style
Saini R, Sharma B, Verma PK, Bhutani G, Rani S. NSAIDS: The Double Edge Sword- Pharmacovigilance In A Tertiary Care Hospital, Int Res Pub Med Sci 2016; 2(3) : 6-10.
Harvard Style
Saini R, Sharma B, Verma PK, Bhutani G, Rani S.(2016) NSAIDS: The Double Edge Sword- Pharmacovigilance In A Tertiary Care Hospital, Int Res Pub Med Sci. 2(3) : 6-10.
Designed By - Innctech Solutions