This to certify that International Research and Publications in Medical Sciences (IRPMS) editorial team has considered to present the best paper award to the corresponding author Kristine Joy G. Boholst, Noli A. Cabildo, David Vi for publishing his outstanding research paper in IRPMS, Volume-3, Issue-4, Oct-Dec entitled as 1. FACTORS FOR TUBERCULOSIS TREATMENT RELAPSE AMONG PATIENTS PREVIOUSLY TAKING CATEGORY 1 STANDARD TUBERCULOSIS TREATMENT REGIMEN IN SELECTED MUNICIPALITIES OF ILOCOS SUR.
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Dr.Jignesh Kothari, Dr.Ramesh Patel, Dr.Hemang Gandhi, Dr.Ajay Chaurasia, Mr.Sanjay Patel, IRPMS, 2015; 1(2): 1-4.
ABSTRACT
Background: Atrial fibrillation occurs in 20%-50% of patients who undergo coronary artery bypass grafting and major cause of increased intensive care unit and hospital costs. This study, therefore assessed the safety, efficacy and benefits of low dose amiodarone in the prevention of post-operative atrial fibrillation after coronary artery bypass grafting. Materials and Methods: One hundred and twenty eight patients who underwent off pump coronary artery bypass grafting during November 2011 to January 2013 received low dose intravenous amiodarone at induction and compared to controls (N=130). A reduction in the incidence of post-operative atrial fibrillation, its duration and the need for other drug combinations for its control were examined. Results: Incidence of post-operative atrial fibrillation in amiodarone treated patients was significantly lesser 13/121 (10.7%) patients as compared to 26/122 (21.3%) controls. The duration of atrial fibrillation, however was similar in both the groups (3.3±1.4 days in patients, 3.5±1.7 days in controls; Mean ±SD). Amiodarone infusion at a dose of 700 mg for the next 24 h in all the patients controlled the heart rate. In the average duration of reversal of atrial fibrillation to sinus rhythm was 4 to 6 h in all these patients. Conclusion: The current study is a demonstration of significant reduction in the number of patients experiencing post-operative atrial fibrillation following peri-operative single intravenous, low dose amiodarone. Further, low dose amiodarone is well tolerated and does not increase risk of intra- and post-operative complications in patients undergoing off pump coronary arterial bypass grafting.
Key words: Off pump coronary artery bypass graft surgery, postoperative atrial fibrillation (POAF), Low dose Amiodarone.
HOW TO CITE THIS ARTICLE:
PubMed Style
Kothari J, Patel R, Gandhi H, Chaurasia A, Patel S. Atrial Fibrillation Following Off-pump Coronary Artery Bypass Graft Surgery: Influence Of Single, Low Dose Amiodarone. IRPMS.2015; 1(2): 1-4.
Web Style
Kothari J, Patel R, Gandhi H, Chaurasia A, Patel S. Atrial Fibrillation Following Off-pump Coronary Artery Bypass Graft Surgery: Influence Of Single, Low Dose Amiodarone. http://irpms.com/home/article_abstract/40 [Access: July 19, 2015].
AMA (American Medical Association) Style
Kothari J, Patel R, Gandhi H, Chaurasia A, Patel S. Atrial Fibrillation Following Off-pump Coronary Artery Bypass Graft Surgery: Influence Of Single, Low Dose Amiodarone. IRPMS. 2015; 1(2): 1-4.
Vancouver/ICMJE Style
Kothari J, Patel R, Gandhi H, Chaurasia A, Patel S. Atrial Fibrillation Following Off-pump Coronary Artery Bypass Graft Surgery: Influence Of Single, Low Dose Amiodarone. IRPMS, 2015; 1(2): 1-4.
Harvard Style
Kothari J, Patel R, Gandhi H, Chaurasia A, Patel S.( 2015)Atrial Fibrillation Following Off-pump Coronary Artery Bypass Graft Surgery: Influence Of Single, Low Dose Amiodarone. IRPMS. 1(2): 1-4.